DeSoto County is a county located on the northwest border of the U.S. state of Mississippi. As of the 2010 census, the population was 161,252, making it the third-most populous county in Mississippi. Its county seat is Hernando.DeSoto County is part of the Memphis, TN-MS-AR Metropolitan Statistical Area. It is the second-most populous county in the MSA. The county has lowland areas that were developed in the 19th century for cotton plantations, and hill country in the eastern part of the county.
Memphis, TN-MS-AR MSA
The Memphis–Forrest City Combined Statistical Area, TN–MS–AR (CSA) is the commercial and cultural hub of The Mid-South or Ark-Miss-Tenn. The census defined combined statistical area covers ten counties in three states – Tennessee, Mississippi, and Arkansas. As of census 2010 the MSA had a population of 1,324,108 . The Forrest City Micropolitan area was added to the Memphis area in 2012 to form the Memphis–Forrest City Combined Statistical area and had a population of 1,369,548 according to census estimates. The greater Mid-South area as a whole has a population of 2.4 million according to 2013 census estimates. This area is covered by Memphis local news channels and includes the Missouri Bootheel, Northeast Arkansas, West Tennessee, and North Mississippi.